Evolution sees the activation of the sympathetic nervous system merely as a short-term reaction and
exception to ensure survival in critical situations. However, the
Reactions of the parasympathetic nervous system as the predominant and primary state of the
organism.
However, sometimes dramatic and revolutionary global and social changes lead to chronic, i.e. permanent stress for many people. This is often accompanied by emotional and psychological stress. These relate to stressful feelings, thoughts and experiences, often with negative effects on mental well-being. Triggers include traumatic events, persistent worries, relationship problems, work pressure and other psychosocial factors.
Chronic stress is often accompanied by so-called sympathicotonia. This describes a condition in which the sympathetic nervous system is overactivated or chronically stimulated. Sympathicotonia has a number of health-critical and negative immunological effects on the body that are associated with silent inflammation and oxidative stress.
Sympathicotonia and silent inflammation
When the sympathetic nervous system is continuously activated, stress hormones such as adrenaline and noradrenaline are released in increased quantities. These hormones can influence the immune system and lead to increased production of pro-inflammatory molecules.
The constant release of these molecules, known as cytokines, even without obvious injury or infection, leads to silent inflammation. This silent inflammation can become entrenched in the body and increase the risk of chronic diseases such as cardiovascular disease, diabetes and neurodegenerative diseases (Alzheimer's, Parkinson's, ALS, etc.). Silent inflammation can also affect the blood-brain barrier, which can lead to inflammation in the central nervous system such as multiple sclerosis.
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